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    The study's primary endpoint is to demonstrate an ORR benefit compared to historical control of 12-15%.

    Twenty-four patients will be enrolled under the first phase of the VAL-083 REPROVe Trial with top line results expected within 18-24 months from trial initiation of patient treatment.

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    Del Mar has demonstrated that VAL-083's mechanism of action is distinct from multiple chemotherapies widely used in the treatment of cancer and that this unique mechanism may offer opportunities to overcome treatment resistance thereby offering new treatment options to cancer patients.

    Further details regarding these studies can be found at Del Mar Pharmaceuticals is focused on the development and commercialization of new therapies for cancer patients who have limited or no treatment options. Based on Del Mar's internal research programs and these prior NCI-sponsored clinical studies, the Company is conducting clinical trials to support the development and commercialization of VAL-083 across multiple oncology indications to solve significant unmet medical needs.

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